Department of Physics, NCU
Limits of chemical sensing of bacterium Escherichia coli
Speaker
Dr. Xiao-Lun Wu
Department of Physics ,University of Pittsburgh
Date 2018.07.24 (Tue)
Time 14:00-15:00
Place S4-625
Abstract:
Using impulsive stimulation we investigated bacterial chemo-response to a trace amount of chemoattractants. We show that enteric E. coli bacterium is capable of single molecular detection, and it takes one to two binding events to trigger a (de)phosphorylation cascade. Such behavior is consistent with the bacterial chemotaxis network being a high-gain device. However, it is unclear how the network discriminates background noises under the high-gain operation.