Colloquium
Department of Physics, NCU
Zebrafish in regeneration research
陳振輝博士 (Dr. Chen-Hui Chen)
中央研究院細胞與個體生物學研究所
(Institute of Cellular and Organismic Biology (ICOB), Academia Sinica)
Date 2020.10.06 (Tue)
Place S4-625
Time 14:00-16:00
Abstract: Unlike mammals, adult teleost zebrafish and urodele amphibians are able to regenerate complex tissues, including the heart, spinal cord, and major appendages. These vertebrate animals may hold the secret to enhance human regenerative capacity. My research program uses zebrafish as a model to understand how and why natural regeneration occurs. We aim to combine advanced cell imaging and genetics with systems-level analyses to uncover principles and mechanisms that drive the cellular and tissue behaviors during complex tissue regeneration. In this talk, I will introduce a new cell imaging platform that we have developed to capture the population dynamics of thousands of cells from live animals. In addition, I will share some unexpected findings from an interdisciplinary study as an example for why we teamed up with physicists to dissect the control mechanisms of wound healing response in adult zebrafish.