Colloquium20190507-Spatial-Spectral Holographic Imaging

Colloquium
Department of Physics, NCU

Spatial-Spectral Holographic Imaging

Speaker
Prof. Yuan Luo (駱遠)
College of Medicine, NTU臺灣大學醫學院

Date 2019.05.07(Tue)
Time 14:00-16:00
Place S4-625

The biggest challenge on the path towards high-dimensional (HD) imaging is obtaining spatial and spectral information of a volumetric sample in real-time. Advances in this field are of vital importance for biology, material sciences, and medical applications. For example, cancer is one of the leading causes of death in the world, thus gaining a mechanistic understanding of cancer cell processes will significantly impact therapies targeting cancer metastasis pathways. Revealing the entire process with its surrounding environment will require real-time HD imaging systems that will open the way for better understanding of cancer onset and tissue morphology. This talk will introduce real-time HD volume holographic imaging systems, which are based on multiplexed volume holographic (MVH) gratings acting as spatial-spectral filters used in conventional optical imaging systems. This allows the acquisition of spatial images with spectral selectivity but without scanning in both transverse and longitudinal directions. In addition, with proper multiplexed holographic pupil engineering, the MVH systems can provide multiple depth-resolved phase-contrast imaging in real time and quantitative phase imaging in a single shot. Furthermore, the talk will address MVH techniques incorporating other state-of-the-art imaging methods to better manipulate light for label-free imaging as well as fluorescence imaging.