陳宣毅

Hsuan-Yi Chen

320中壢市中大路300號中央大學物理系

(03)4227157 ext 65367

(03)4251175

軟物質與生物物理研究室

Soft matter and Biophysics

hschen@phy.ncu.edu.tw

現 職:

國立中央大學物理學系教授（2010/08∼）

學 歷:

美國匹茲堡大學物理學系博士(2000/04)

國立台灣大學物理學系學士(1992/06)

經 歷:

美國加州大學聖塔芭芭拉分校-材料研究實驗室-博士後研究員(2000/08~2001/08)

國立中央大學物理系助理教授（2001/07∼2006/07）

國立中央大學物理系副教授（2006/08∼2010/07）

研究領域 :

Statistical Physics

Theoretical Soft Condensed Matter Physics

研究著作 :

Journal Publications

1.     Free energy and critical force for adhesion clusters, Han-Jou Lin, Hsuan-Yi Chen, Yu-Jane Sheng, and Heng-Kwong Tsao, submitted to Phys. Rev. E,(2009).

2.     Dynamics of biomembranes with active multiple-state inclusions, Hsuan-Yi Chen and A.S. Mikhailov, accepted by Phys. Rev. E (2010).

3.     Adhesion-induced lateral phase separation of multicomponent membranes: The effect of repellers and confinement, M. Asfaw and Hsuan-Yi Chen, Phys. Rev. E, 79, 041917 (2009).

4.     Forced dissociation of a biomolecular complex under periodic and correlated random forcing, Han-Jou Lin, Yu-Jane Sheng, Hsuan-Yi Chen, and Heng-Kwong Tsao, J. Chem. Phys., 128, 084708 (2008).

5.     Adsorption-induced vesicle fission, Feng-Ching Tsai and Hsuan-Yi Chen, Phys. Rev. E, 78, 051906 (2008).

6.     Flocking states of self-propelling particles in free space, Kwan-Tai Leung and Hsuan-Yi Chen, Int. J. Mod. Phys. B, 21, 3954 (2007).

7.     Lifetime of ligand-receptor clusters under external force, Yi-Ping Chu, Chih-Chao-Tang, and Hsuan-Yi Chen, Physical Review E, 76,061905 (2007).

8.     Influences of Linkage Stiffness on Rupture Rate in Single-Molecule Pulling Experiments, Han-Jou Lin, Yu-Jane Sheng, Hsuan-Yi Chen, and Heng-Kwong Tsao, J. Phys. Chem. B, 111, 6493 (2007).

9.     Bell’s expression and generalized Garg’s form for forced dissociation of a biomolecular complex, Han-Jou Lin, Hsuan-Yi Chen, Yu-Jane Sheng, and Heng-Kwong Tsao, Phys. Rev. Lett., 98, 088304 (2007).

10.   Finite-size domains in active membranes with two-state inclusions, Chien-Hsun Chen and Hsuan-Yi Chen, Phys. Rev. E 74, 051917 (2006).

11.   Stepped changes of monovalent ligand-binding force during ligand-induced clustering of integrin a_IIbb_III, Chia-Fen Hsieh, Bo-Jui Chang, Chyi-Huey Pai, Hsuan-Yi Chen, Jin-We Tsai, Yung-Hsian Yih, Yi-Ting Chian, Da-Wei Wang, Sien Chi, Long Hsu, and Chi-Hung Lin, J. Bio. Chem. 281, 25466 (2006).

12.   Rotating states of two-dimensional self-propelling particles, Hsuan-Yi Chen and Kwan-Tai Leung, Phys. Rev. E 73, 056107 (2006).

13.   Membrane-adhesion-induced phase separation of two species of junctions, Jia-Yuan Wu and Hsuan-Yi Chen, 73, Phys. Rev. E 73, 011914 (2006).

14.   Theoretical determination of the strength of soft noncovalent molecular bonds, Hsuan-Yi Chen and Yi-Ping Chu, Phys. Rev. E 71, 010901(R) (2005).

15.   Internal states of active inclusions and the dynamics of an active membrane, Hsuan-Yi Chen, Phys. Rev. Lett., 92, 168101, (2004).

16.   Adhesion-induced phase separation of multiple species of membrane junctions, Hsuan-Yi Chen, Phys. Rev. E., 67, 031919, (2003).

17.   Morphologies of symmetric ABC triblock copolymer thin films, Hsuan-Yi Chen and G.H. Fredrickson, J. Chem. Phys., 116, 1137 (2002).

18.   Spinodal Decomposition of a Binary Fluid with Fixed Impurities, F. Qiu, G. Peng, V. V. Ginzburg, A.C. Balaz, Hsuan-Yi Chen, and D. Jasnow, J. Chem. Phys. 115, 3779 (2001).

19.   Shear instabilities of freely standing smectic-A films, Hsuan-Yi Chen and D. Jasnow, Phys. Rev. Lett. 85, 2957 (2000)

20.   Interface and contact line motion in a two phase fluid under shear flow, Hsuan-Yi Chen, D. Jasnow, and J. Vinals, Phys. Rev. Lett. 85, 1686 (2000)

21.   Layer dynamics of freely standing smectic-A films, Hsuan-Yi Chen and D. Jasnow, Phys. Rev. E 61, 493, (2000).

22.   Surface dynamics of a freely standing smectic-A film, Hsuan-Yi Chen and D. Jasnow, Phys. Rev. E, 57, 5639, (1998).

23.   Quantum Monte Carlo simulation of a particle in a random potential, Hsuan-Yi Chen and Y.Y. Goldschmidt, J. Phys. A, 30 1803, (1997).

Conference proceedings:

24.   Idnefication of stepped changes of binding affinity during interactions between the disintegrin rodostomin and integrin a_IIbb_III in living cells using optical tweezers, Chia-Fen Hsieh, Bo-Jui Chang, Chyi-Huey Pai, Hsuan-Yi Chen, Sien Chi, Long Hsu, and Chi-Hung Lin, Proc. SPIE, 5514, 215 (2004).

Other publications

1.     Physics of cell motility, Hsuan-Yi Chen, (in Chinese) Physics Bimonthly, December 2007, p1029.

2.     Swimming, escaping from a potential well, and search in cellular scale, Hsuan-Yi Chen, (in Chinese) Physics Bimonthly, August 2006, p685.

3.     Brownian motion: from random walk to biology and astronomy, Hsuan-Yi Chen, (in Chinese) Physics Bimonthly, June 2005, p453..

4.     Editor: Physics Bimonthly, June 2005 (in Chinese)

5.     Block copolymer thin films: self-assembled new materials, Hsuan-Yi Chen, (In Chinese) Physics bimonthly, April 2002, p343.

6.     Dynamics and instabilities of freely standing smectic-A films, Hsuan-Yi Chen, PhD thesis, University of Pittsburgh, April 2000.

Invited talks

1.     Biomembranes containing proteins that like curvature, invited talk at Annual Meeting of Mathematical Society, National Chung-Chen University, 2009.12.

2.     Dynamics of biomembranes with active multiple-state inclusions, invited talk at “Collective dynamics and pattern formation in active matter systems” conference, Humboldt University, Berlin, Germany, 2009.11.

3.     Biology-inspired physics, invited talk at Taiwan-France Frontier of Science Symposium, St. Malo, France, 2009.06

4.     Thermodynamics, lecture in the 4th High School Science Education Program, Academia Sinica, Taipei, 2009.05

5.     The physics of cell adhesion and cell movement, colloquium talk at Department of Physics, Chung-Yuan Christian University 2009.05.

6.    The physics of cell adhesion and cell movement, colloquium talk at the Institute of Physics, Academia Sinica 2009.04.

7.    Bio-soft interfaces, invited talk at Annual Meeting of Chinese Physical Society, National Cang-Hua Normal University, 2009.01.

8.    Modeling biomembranes that contain active proteins, invited talk at International Workshop on Mathematical Biology: Modeling and Analysis, National Taiwan Normal University, Taipei, 2008.12.

9.    Statistical mechanics of reversible non-covalent bonds: from single molecule experiment to cell adhesion, seminar at 2008 NCTS December Workshop on Critical Phenomena and Complex Systems, Chinese Culture University, Taipei, 2008.12.

10.  Active soft matter: filaments, membranes, and gels, invited seminar at Department of Physics, NTHU, 2008.10.

11.  Active soft matter, invited seminar at Institute of Physics, Academia Sinica, 2008.10.

12.  Thermodynamics, lecture in the 4th High School Science Education Program, Academia Sinica, Taipei, 2008.10.

13.  Dynamics of membrane with anchored active proteins, invited talk at International Workshop on Bio Soft Matter 2008, University Tokyo, Tokyo, Japan, 2008.06.

14.  Statistical mechanics of reversible non-covalent bonds: from single molecule experiment to cell adhesion, seminar at Department of Chemistry, Tokyo Metropolitan University, Tokyo, Japan, 2008.06

15.  Force-induced oscillations of polymerizing actin gels, invited talk at the 13^th Joint Biophysics Conference, National Chung University, Hui-Sun Forest Station, Nantou, Taiwan. 2008.05.

16.  Dynamics of membrane with anchored proteins, invited talk at 2008 NCTS March Workshop on Critical Phenomena and Complex Systems, Taipei, 2008. 03.

17.  Kinetics of adsorption-induced vesicle fission, invited talk at Annual Meeting of Chinese Physical Society, National Chiao Tung University, 2008.01.

18.   From single molecule experiments to cell adhesion, colloquium at Department of Physics, NCUE, 2008.01.

19.   Non-equilibrium domains in lipid membranes, invited talk at 2007 Winter Workshop on Low Dimensional Systems and Nanostructures, Tunghai University, Taiwan, 2007.12.

20.   Thermodynamics, lecture in the 3rd High School Science Education Program, Academia Sinica, Taipei, 2007.06.

21.   Free energy landscape and lifetime of parallel bonds, invited talk at 2007 Taipei International Workshop for Soft Matter and Biophysics, Academia Sinica, Taipei. 2007, 05.

22.   Free energy landscape of parallel soft bonds, seminar at nonlinear dynamics group, Department of Physics, Kyoto University, Japan, 2007.05.

23.   Brownian and modern physics, talk at Taipei private Wego senior high school, 2007.04.

24.  Nano-bio adhesion, colloquium at Institute of Physics, NCTU, 2007.04.

25.  Lifetime of ligand-receptor clusters under external force, invited talk at International Symposium on the Recent Progress in Quantitative and Systems Biology. The Chinese University of Hong Kong, Hong Kong, 2006.12.

26.  Models of non-equilibrium domains in membranes, seminar “Complex Nonlinear Processes in Chemisry and Biology” at Fritz-Haber-Institut der Max-Planck-Gesellschaft, Berlin, Germany, 2006.10.

27.   Probing the strength of ligand/receptor pairs and ligand/receptor clusters. Seminar at nonlinear dynamics group, Department of Physics, Kyoto University, Japan, 2006.09.

28.   On the strength of soft biomolecular bonds, talk at the 8th Taiwan International Symposium on Statistical Physics. Academia Sinica, Taipei, Taiwan, 2006.06

29.   Theoretical tools to study active bio-soft matter systems, talk at 5th BITS, Taichung, Taiwan, 2006.06.

30.   Biological membranes as active soft matter, colloquium at Department of Physics, National Cheng-Kung University, Taiwan, 2006.05

31.   Breaking soft bonds, colloquium at Department of Physics, National Chung-Hsing University, Taiwan,  2005.12.

32.   Bio-adhesion on sub-cellular scale, colloquium at Department of Chemical and Materials Engineering, National Central University, 2005.12.

33.   Rotating states of two-dimensional self-propelling particles, talk at 2005 Regional Bio-Soft Matter Days, Taipei, 2005.12.

34.   Active membranes with two-state active inclusions, seminar at Focus Program on Biopolymers and Cell Dynamics II, in Asia-Pacific Center for Theoretical Physics, Pohang, Korea, 2005.11.

35.   The morphologies of active membranes, talk at 2005 Workshop on nonlinear phenomena, Chi-Tou, 2005.08.

36.   From E. Coli to Lion King, talk at High school summer camp, National Science and Technology Museum, 2005.08.

37.   Animal groups in motion: moving flocks, vortices, and rotating rings, seminar at Physics Division, National Center for Theoretical Sciences, 2005.03.

38.   Ideas on ligand-receptor adhesion and membrane adhesion, colloquium at Department of Physics, National Taiwan Normal University, 2004.12.

39.   Modeling active membranes, seminar at Physics Division, National Center for Theoretical Sciences, 2004.05.

40.   Modeling active membranes, talk at 2004 Taipei Spring Workshop on Statistical and Nonlinear Physics, National Center for Theoretical Sciences, Taipei. 2004.03.

41.   Modeling biomembranes, colloquium at Department of Chemical Engineering, National Taiwan University, 2004.02.

42.   Frustration: some of its applications in complex fluids, seminar at Materials Science and Technology Program, National Taiwan University of Science and Technology, 2002.11.

研究計畫 :